Although the job situation and the system of part time

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Transient transfection of periplakin deletion constructs indicated that the first 133 amino acid residues are essential for the co localisation with plectin at cell borders. Immunofluorescence analysis demonstrated that periplakin N terminus and different plectin isoforms steroids, such as plectin 1, 1 f and 1k steroids, are co localise at cell borders of MCF 7 epithelia and also co localise with endogenous periplakin at suprabasal layers of the skin. Ablation of the plectin by siRNA transfection in HaCaT keratinocytes resulted in aggregation of periplakin into small clusters in the cytoplasm.

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